Abcam, ab143368, Brivudine, pyrimidine nucleoside analog

Size: 10mg
MW 333.13 Da. Pyrimidine nucleoside analog. Antiviral agent (IC 50 values are 76 nM and 1.4 μM for herpesvirus and HIV respectively). Blocks DNA polymerase. Binds to heat shock protein HSPB1 and inhibits interaction with its binding partners. Shows anticancer effects in vivo . Orally active.
Key facts
Molecular weight:333.13 Da,
Molecular formula:C11H13BrN2O5,
PubChem:3183,
Nature:Synthetic,
Biochemical name:5-(2-Bromoethenyl)-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione,
Biological description:Pyrimidine nucleoside analog. Antiviral agent (IC50 values are 76 nM and 1.4 μM for herpesvirus and HIV respectively). Blocks DNA polymerase. Binds to heat shock protein HSPB1 and inhibits interaction with its binding partners. Shows anticancer effects in vivo. Orally active.,
Canonical smiles:C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O,
InChi:InChI=1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18),
InChiKey:ODZBBRURCPAEIQ-UHFFFAOYSA-N,
IUPAC Name:5-(2-bromoethenyl)-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months