Abcam, ab144291, Latrunculin B, actin polymerization inhibitor

Size: 1mg
MW 395.5 Da, Purity >96%. Cell-permeable actin polymerization inhibitor. Forms a 1:1 complex with monomeric G-actin. Shows less potent growth inhibition effects on cancer cell lines than Latrunculin A, (ab144290) (IC 50 values are 7.1 and 4.8 μM for HCT116 and MDA-MB-435 cells respectively). Shows antiglaucoma effects in vivo. .
Key facts
CAS number:76343-94-7,
Purity:>96%,
Form:SolidSee storage information,
Source:Latrunculia magnifica,
Molecular weight:395.5 Da,
Molecular formula:C20H29NO5S,
PubChem:6436219,
Nature:Native,
Solubility:Soluble in DMSO (25 mg/ml)Soluble in ethanol (25 mg/ml),
Biochemical name:latrunculin B,
Biological description:Cell-permeable actin polymerization inhibitor. Forms a 1:1 complex with monomeric G-actin. Shows less potent growth inhibition effects on cancer cell lines than Latrunculin A, (ab144290) (IC50 values are 7.1 and 4.8 μM for HCT116 and MDA-MB-435 cells respectively). Shows antiglaucoma effects in vivo.,
Canonical smiles:CC1CCC2CC(CC(O2)(C3CSC(=O)N3)O)OC(=O)C=C(CCC=C1)C,
Isomeric smiles:C[C@H]/1CC[C@@H]2C[C@H](C[C@@](O2)([C@@H]3CSC(=O)N3)O)OC(=O)/C=C(\CC/C=C1)/C,
InChi:InChI=1S/C20H29NO5S/c1-13-5-3-4-6-14(2)9-18(22)25-16-10-15(8-7-13)26-20(24,11-16)17-12-27-19(23)21-17/h3,5,9,13,15-17,24H,4,6-8,10-12H2,1-2H3,(H,21,23)/b5-3-,14-9-/t13-,15-,16-,17+,20-/m1/s1,
InChiKey:NSHPHXHGRHSMIK-JRIKCGFMSA-N,
IUPAC Name:(4R)-4-[(1R,4Z,8Z,10S,13R,15R)-15-hydroxy-5,10-dimethyl-3-oxo-2,14-dioxabicyclo[11.3.1]heptadeca-4,8-dien-15-yl]-1,3-thiazolidin-2-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions