Abcam, ab144316, NSC697923, UBE2N inhibitor

Size: 1mg / 5mg / 25mg
MW 267.26 Da, Purity >98%. Selective, cell-permeable UBE2N inhibitor. Inhibits E2 complex Ubc13-Uev1A. Inhibits NF-κB activation. Induces nuclear accumulation of p53 and apoptosis. Shows potent cytotoxic effects to neuroblastoma cell lines. Shows antitumor effects in vivo. .
Key facts
CAS number:343351-67-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:267.26 Da,
Molecular formula:C11H9NO5S,
PubChem:394449,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mM (with gentle warming)Soluble in DMSO to 100 mM,
Biochemical name:2-[(4-Methylphenyl)sulfonyl]-5-nitrofuran,
Biological description:Selective, cell-permeable UBE2N inhibitor. Inhibits E2 complex Ubc13-Uev1A. Inhibits NF-κB activation. Induces nuclear accumulation of p53 and apoptosis. Shows potent cytotoxic effects to neuroblastoma cell lines. Shows antitumor effects in vivo.,
Canonical smiles:CC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O2)[N+](=O)[O-],
InChi:InChI=1S/C11H9NO5S/c1-8-2-4-9(5-3-8)18(15,16)11-7-6-10(17-11)12(13)14/h2-7H,1H3,
InChiKey:GAUHIPWCDXOLCZ-UHFFFAOYSA-N,
IUPAC Name:2-(4-methylphenyl)sulfonyl-5-nitrofuran

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions