Abcam, ab144440, Dimethoxycurcumin, curcumin analog

Size: 5mg / 10mg
MW 396.4 Da, Purity >90%. Metabolically more stable curcumin (ab120618, ab141921) analog. Antiproliferative agent. Induces non-cytotoxic G2/M phase cell cycle arrest and apoptosis. Induces the expression of promoter methylated genes. Inhibits NO production, iNOS expression and NF-κB activation. Shows antiproliferative effects (IC 50 = 0.5-1 μM).
Key facts
CAS number:160096-59-3,
Purity:>90%,
Molecular weight:396.4 Da,
Molecular formula:C23H24O6,
PubChem:9952605,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:Dimethoxycurcumin,
Biological description:Metabolically more stable curcumin (ab120618, ab141921) analog. Antiproliferative agent. Induces non-cytotoxic G2/M phase cell cycle arrest and apoptosis. Induces the expression of promoter methylated genes. Inhibits NO production, iNOS expression and NF-κB activation. Shows antiproliferative effects (IC50 = 0.5-1 μM).,
Canonical smiles:COC1=C(C=C(C=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)OC)OC)OC,
Isomeric smiles:COC1=C(C=C(C=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)OC)OC)OC,
InChi:InChI=1S/C23H24O6/c1-26-20-11-7-16(13-22(20)28-3)5-9-18(24)15-19(25)10-6-17-8-12-21(27-2)23(14-17)29-4/h5-14H,15H2,1-4H3/b9-5+,10-6+,
InChiKey:HMJSBVCDPKODEX-NXZHAISVSA-N,
IUPAC Name:(1E,6E)-1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months