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BRAND / VENDOR: Abcam

Abcam, ab144443, GW 590735, PPARalpha agonist

CATALOG NUMBER: ab144443
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Product Description

Size: 1mg / 5mg / 10mg / 25mg
MW 478.5 Da, Purity >98%. Potent, selective PPARα agonist (EC 50 = 4 nM). Increases HDL cholesterol, decreases LDL and VLDL cholesterol. Reduces triglycerides. Shows antidyslipidemic effects in vivo. .
Key facts
CAS number:343321-96-0,
Purity:>98%,
Molecular weight:478.5 Da,
Molecular formula:C23H21F3N2O4S,
PubChem:9956726,
Nature:Synthetic,
Solubility:Soluble in ethanol to 50 mMSoluble in DMSO to 50 mM,
Biochemical name:2-Methyl-2-(4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxamido)methyl)phenoxy)propanoic acid,
Biological description:Potent, selective PPARα agonist (EC50 = 4 nM). Increases HDL cholesterol, decreases LDL and VLDL cholesterol. Reduces triglycerides. Shows antidyslipidemic effects in vivo.,
Canonical smiles:CC1=C(SC(=N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NCC3=CC=C(C=C3)OC(C)(C)C(=O)O,
InChi:InChI=1S/C23H21F3N2O4S/c1-13-18(33-20(28-13)15-6-8-16(9-7-15)23(24,25)26)19(29)27-12-14-4-10-17(11-5-14)32-22(2,3)21(30)31/h4-11H,12H2,1-3H3,(H,27,29)(H,30,31),
InChiKey:ILUPZUOBHCUBKB-UHFFFAOYSA-N,
IUPAC Name:2-methyl-2-[4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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Collaboration

Tony Tang

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