Abcam, ab144595, C16, PKR inhibitor

Size: 5mg / 25mg
MW 268.3 Da, Purity >98%. Specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. Prevents PKR-induced neuronal loss in vivo . Inhibits apoptotic PKR/eIF2α signaling pathway in vivo . Neuroprotective, antitumor and anti-inflammatory agent. Active in vivo and in vitro .
Key facts
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:268.3 Da,
Molecular formula:C13H8N4OS,
PubChem:67016828,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:8-(1h-Imidazol-4-ylmethylene)-6,8-dihydrothiazolo[5,4-e]indol-7-one,
Biological description:Specific double-stranded RNA-dependent protein kinase (PKR) inhibitor. Prevents PKR-induced neuronal loss in vivo. Inhibits apoptotic PKR/eIF2α signaling pathway in vivo. Neuroprotective, antitumor and anti-inflammatory agent. Active in vivo and in vitro.,
Canonical smiles:C1=CC2=C(C3=C1NC(=O)C3=CC4=CN=CN4)SC=N2,
Isomeric smiles:C1=CC2=C(C\3=C1NC(=O)/C3=C/C4=CN=CN4)SC=N2,
InChi:InChI=1S/C13H8N4OS/c18-13-8(3-7-4-14-5-15-7)11-9(17-13)1-2-10-12(11)19-6-16-10/h1-6H,(H,14,15)(H,17,18)/b8-3+,
InChiKey:VFBGXTUGODTSPK-FPYGCLRLSA-N,
IUPAC Name:(8E)-8-(1H-imidazol-5-ylmethylidene)-6H-pyrrolo[2,3-g][1,3]benzothiazol-7-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months