Abcam, ab144655, Ro 106-9920, NF-kappaB inhibitor

Size: 10mg / 50mg
MW 245.26 Da, Purity >95%. NF-κB inhibitor. Anti-inflammatory agent. Selectively inhibits LPS- and TNF-α-induced IκBα ubiquitination (IC 50 = 3 μM). Inhibits TNF-α, IL-1β and IL-6 production. Shows anti-inflammatory effects in vivo. Orally active.
Key facts
CAS number:62645-28-7,
Purity:>95%,
Form:SolidSee storage information,
Molecular weight:245.26 Da,
Molecular formula:C10H7N5OS,
PubChem:3906779,
Nature:Synthetic,
Solubility:Soluble in ethanol to 10 mMSoluble in DMSO to 100mM,
Biochemical name:6-(Benzenesulfinyl)tetrazolo[1,5-b]pyridazine,
Biological description:NF-κB inhibitor. Anti-inflammatory agent. Selectively inhibits LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Inhibits TNF-α, IL-1β and IL-6 production. Shows anti-inflammatory effects in vivo. Orally active.,
Canonical smiles:C1=CC=C(C=C1)S(=O)C2=NN3C(=NN=N3)C=C2,
InChi:InChI=1S/C10H7N5OS/c16-17(8-4-2-1-3-5-8)10-7-6-9-11-13-14-15(9)12-10/h1-7H,
InChiKey:JFSXSNSCPNFCDM-UHFFFAOYSA-N,
IUPAC Name:6-(benzenesulfinyl)tetrazolo[1,5-b]pyridazine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions