Abcam, ab145048, SecinH3, Sec7-GEF inhibitor

Size: 10mg / 50mg
MW 460.5 Da, Purity >99%. Selective Sec7-GEF inhibitor (IC 50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, Drosophila steppke, yGea2-S7 and hEFA6-S7, respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein phosphorylation. Cell-permeable.
Key facts
CAS number:853625-60-2,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:460.5 Da,
Molecular formula:C24H20N4O4S,
PubChem:1029232,
Nature:Synthetic,
Solubility:Soluble in ethanol to 10 mMSoluble in DMSO to 100 mM,
Biochemical name:SecinH3,
Biological description:Selective Sec7-GEF inhibitor (IC50 values are 2.4, 5.4, 5.4, 5.6, 5.6, 65 and > 100 μM for hCyh2, hCyh1, mCyh3, hCyh3, Drosophila steppke, yGea2-S7 and hEFA6-S7, respectively). Inhibits insulin signaling via inhibition of insulin receptor substrate protein phosphorylation. Cell-permeable.,
Canonical smiles:COC1=NN(C(=N1)C2=CC3=C(C=C2)OCO3)C4=CC=C(C=C4)NC(=O)CSC5=CC=CC=C5,
InChi:InChI=1S/C24H20N4O4S/c1-30-24-26-23(16-7-12-20-21(13-16)32-15-31-20)28(27-24)18-10-8-17(9-11-18)25-22(29)14-33-19-5-3-2-4-6-19/h2-13H,14-15H2,1H3,(H,25,29),
InChiKey:QPGYAMIHXLCFTJ-UHFFFAOYSA-N,
IUPAC Name:N-[4-[5-(1,3-benzodioxol-5-yl)-3-methoxy-1,2,4-triazol-1-yl]phenyl]-2-phenylsulfanylacetamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months