Abcam, ab145523, PD 151746, Calpain inhibitor

Size: 5mg / 25mg
MW 237.25 g/mol, Purity >96%. Cell permeable, selective, non-peptidic calpain inhibitor (K i values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca 2+ calpain sites. Shows antiapoptotic effects.
Key facts
CAS number:179461-52-0,
Purity:>96%,
Form:SolidSee storage information,
Molecular weight:237.25 g/mol,
Molecular formula:C11H8FNO2S,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biological description:Cell permeable, selective, non-peptidic calpain inhibitor (Ki values are 0.3 and 5 μM for calpain 1 and calpain 2, respectively). Stimulates phagocyte function via hFPR/hFPRL1 activation. Interacts with the Ca2+ calpain sites. Shows antiapoptotic effects.,
Canonical smiles:C1=CC2=C(C=C1F)C(=CN2)C=C(C(=O)O)S,
InChi:InChI=1S/C11H8FNO2S/c12-7-1-2-9-8(4-7)6(5-13-9)3-10(16)11(14)15/h1-5,13,16H,(H,14,15)/b10-3-,
InChiKey:HWMQHECFXSVZGN-KMKOMSMNSA-N,
IUPAC Name:3-(5-Fluoro-1H-indol-3-yl)-2-mercapto-2-propenoic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store in the dark, Store under desiccating conditions, This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes