Abcam, ab145601, MDL 28170 (Calpain Inhibitor III), calpain and cathepsin B inhibitor

Size: 10mg / 50mg
MW 382.5 Da, Purity >95%. Potent and selective cell-permeable calpain and cathepsin B inhibitor (IC 50 = 11 nM, calpain, K i values are 10 and 25 nM for calpain and cathepsin B respectively). Shows neuroprotective effects in vivo . Blood-brain barrier permeable.
Key facts
CAS number:88191-84-8,
Purity:>95%,
Molecular weight:382.5 Da,
Molecular formula:C22H26N2O4,
PubChem:9907994,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Z-Val-Phe-CHO,
Biological description:Potent and selective cell-permeable calpain and cathepsin B inhibitor (IC50 = 11 nM, calpain, Ki values are 10 and 25 nM for calpain and cathepsin B respectively). Shows neuroprotective effects in vivo. Blood-brain barrier permeable.,
Canonical smiles:CC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2,
InChi:InChI=1S/C22H26N2O4/c1-16(2)20(24-22(27)28-15-18-11-7-4-8-12-18)21(26)23-19(14-25)13-17-9-5-3-6-10-17/h3-12,14,16,19-20H,13,15H2,1-2H3,(H,23,26)(H,24,27),
InChiKey:NGBKFLTYGSREKK-UHFFFAOYSA-N,
IUPAC Name:benzyl N-[3-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]butan-2-yl]carbamate

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2195 MDL 28170. 2195-50 is the same size as the 50 mg size of ab145601.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions|The product can be stored for up to 12 months