Abcam, ab145624, AT 101, Bcl-2 and Mcl-1 inhibitor (BH3-mimetic)

Size: 5mg
MW 518.56 g/mol, Purity >98%. Pro-apoptotic agent. BH3-mimetic. Bcl-2 and Mcl-1 inhibitor. Gossypol (ab141050, ab144391) enantiomer. Induces Noxa and PUMA. Shows antiproliferative and chemosensitizing effects in vivo. Orally active.
Key facts
CAS number:90141-22-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:518.56 g/mol,
Nature:Synthetic,
Solubility:Soluble in ethanol to 75 mMSoluble in DMSO to 75 mM,
Biological description:Pro-apoptotic agent. BH3-mimetic. Bcl-2 and Mcl-1 inhibitor. Gossypol (ab141050, ab144391) enantiomer. Induces Noxa and PUMA. Shows antiproliferative and chemosensitizing effects in vivo. Orally active.,
Canonical smiles:OC1=C(O)C(C(C)C)=C(C=C(C)C(C2=C(O)C(C(C([H])=O)=C(O)C(O)=C3C(C)C)=C3C=C2C)=C4O)C4=C1C([H])=O,
InChi:InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3,
InChiKey:QBKSWRVVCFFDOT-UHFFFAOYSA-N,
IUPAC Name:(R)-1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)-[2,2'-binaphthalene]-8,8'-dicarboxaldehyde

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2380 AT-101. 2380-25 is the same size as the 25 mg size of ab145624.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months