Abcam, ab145857, VGX-1027 (Git-27), TLR4 inhibitor

Size: 5mg / 25mg
MW 205.21 Da, Purity >98%. Immunomodulatory agent. TLR4 inhibitor. TLR4 and TLR 2/6 signaling pathway modulator. Inhibits inflammatory antigen presentation. Inhibits IL1-β, IL-10, IFN-γ and TNF-α secretion. Shows anti-inflammatory effects in vivo. Orally active.
Key facts
CAS number:6501-72-0,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:205.21 Da,
Molecular formula:C11H11NO3,
PubChem:10798271,
Nature:Synthetic,
Solubility:Soluble in ethanol to 50 mMSoluble in DMSO to 25 mM,
Biochemical name:4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid,
Biological description:Immunomodulatory agent. TLR4 inhibitor. TLR4 and TLR 2/6 signaling pathway modulator. Inhibits inflammatory antigen presentation. Inhibits IL1-β, IL-10, IFN-γ and TNF-α secretion. Shows anti-inflammatory effects in vivo. Orally active.,
Canonical smiles:C1C(ON=C1C2=CC=CC=C2)CC(=O)O,
InChi:InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14),
InChiKey:MUFJHYRCIHHATF-UHFFFAOYSA-N,
IUPAC Name:2-(3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months