Abcam, ab146030, Cyclic pifithrin-alpha-p-nitro, transcriptional p53 inhibitor

Size: 5mg
MW 299.3 Da, Purity >99%. Cell-permeable transcriptional p53 inhibitor. Shows potent neuroprotective effects (ED 50 = 30 nM, etoposide-induced cortical neuron death). Shows a 50% longer half-life than Pifithrin-α (ab120478).
Key facts
CAS number:60477-38-5,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:299.3 Da,
Molecular formula:C15H13N3O2S,
PubChem:4587369,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:2-(4-Nitrophenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole,
Biological description:Cell-permeable transcriptional p53 inhibitor. Shows potent neuroprotective effects (ED50 = 30 nM, etoposide-induced cortical neuron death). Shows a 50% longer half-life than Pifithrin-α (ab120478).,
Canonical smiles:C1CCC2=C(C1)N3C=C(N=C3S2)C4=CC=C(C=C4)[N+](=O)[O-],
InChi:InChI=1S/C15H13N3O2S/c19-18(20)11-7-5-10(6-8-11)12-9-17-13-3-1-2-4-14(13)21-15(17)16-12/h5-9H,1-4H2,
InChiKey:XMFNSEDROOHGBY-UHFFFAOYSA-N,
IUPAC Name:2-(4-nitrophenyl)-5,6,7,8-tetrahydroimidazo[2,1-b][1,3]benzothiazole

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions