Abcam, ab146177, Fascaplysin, ATP-competitve CDK4 inhibitor

Size: 1mg / 5mg
MW 306.75 g/mol. Potent, selective ATP-competitive CDK4 inhibitor (IC 50 = 350 nM). Suppresses VEGF expression and inhibits endothelial cell proliferation. Induces apoptosis and cytotoxic autophagy in vitro .
Key facts
CAS number:114719-57-2,
Form:SolidSee storage information,
Molecular weight:306.75 g/mol,
Molecular formula:C18H11ClN2O,
Nature:Synthetic,
Biological description:Potent, selective ATP-competitive CDK4 inhibitor (IC50 = 350 nM). Suppresses VEGF expression and inhibits endothelial cell proliferation. Induces apoptosis and cytotoxic autophagy in vitro.,
Canonical smiles:[CL-].O=C4C1CCCCC1[N+]5CCC2C(NC3CCCCC23)C45,
InChi:InChI=1S/C18H10N2O.ClH/c21-18-13-6-2-4-8-15(13)20-10-9-12-11-5-1-3-7-14(11)19-16(12)17(18)20;/h1-10H;1H,
InChiKey:PWUOOJVYZQILBG-UHFFFAOYSA-N

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months