Abcam, ab146187, LM11A-31, nonpeptide p75NTR ligand

Size: 5mg / 25mg
MW 316.26 Da. Selective nonpeptide p75NTR ligand. Blocks p75-mediated cell death. Promotes neurogenesis and neurite survival. Does not affect NGF binding to TrkA. Shows neuroprotective and neuroregenerative effects *in vivo.* Orally active. Blood-brain barrier permeable.
Key facts
CAS number:1243259-19-9,
Molecular weight:316.26 Da,
Molecular formula:C12H27Cl2N3O2,
PubChem:91654620,
Nature:Synthetic,
Solubility:Soluble in water to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:LM11A-31 Dihydrochloride,
Biological description:Selective nonpeptide p75NTR ligand. Blocks p75-mediated cell death. Promotes neurogenesis and neurite survival. Does not affect NGF binding to TrkA. Shows neuroprotective and neuroregenerative effects *in vivo.* Orally active. Blood-brain barrier permeable.,
Canonical smiles:CCC(C)C(C(=O)NCCN1CCOCC1)N.Cl.Cl,
Isomeric smiles:CC[C@H](C)[C@@H](C(=O)NCCN1CCOCC1)N.Cl.Cl,
InChi:InChI=1S/C12H25N3O2.2ClH/c1-3-10(2)11(13)12(16)14-4-5-15-6-8-17-9-7-15;;/h10-11H,3-9,13H2,1-2H3,(H,14,16);2*1H/t10-,11-;;/m0../s1,
InChiKey:LLIHJRRZJDEKLB-ULEGLUPFSA-N,
IUPAC Name:(2S,3S)-2-amino-3-methyl-N-(2-morpholin-4-ylethyl)pentanamide;dihydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months