Abcam, ab155089, Anti-FABP12 antibody [EPR10536]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal FABP12 antibody. Suitable for WB, ICC/IF, Flow Cyt (Intra) and reacts with Human, Rat, Mouse samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR10536,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:Flow Cyt (Intra), WB, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
FABP12 also known as fatty acid-binding protein 12 plays a role in lipid transport and metabolism. This protein facilitates the binding and transport of long-chain fatty acids within cells. Although its exact molecular weight is not universally established similar fatty acid-binding proteins often have masses around 14-15 kDa. FABP12 expression primarily occurs in the mammalian retina with detectable levels in other tissues including certain types of cancer tissues.
Biological function summary
FABP12 influences cellular processes through its interaction with lipids. This protein contributes to fatty acid uptake and intracellular lipid homeostasis. It does not function as part of a larger macromolecular complex but interacts dynamically with fatty acids impacting lipid signaling and energy balance within the cell. Through these interactions FABP12 supports cellular energy production and lipid storage regulation.
Pathways
FABP12 is involved in lipid metabolism and energy homeostasis pathways. One important pathway includes the peroxisome proliferator-activated receptor (PPAR) signaling pathway which regulates lipid metabolism. Nearby proteins like PPAR-alpha and PPAR-gamma are important for FABP12’s regulation of lipid-derived energy. Another relevant connection is to the retinoic acid signaling pathway where FABP12’s binding affinity with retinoids potentially influences cellular differentiation and development.
Research connects FABP12 to cancer and metabolic syndromes. In some cancers altered expression levels of FABP12 appear to influence tumor growth and metabolism. Studies have linked FABP12 with proteins such as FABP5 another member of the fatty acid-binding protein family in cancerous tissue dynamics. Additionally FABP12 involvement in metabolic disorders suggests a relationship with insulin resistance where its expression may impact the function of key proteins related to glucose metabolism.