Abcam, ab167167, Anti-OTOP2 antibody [EPR9484]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal OTOP2 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR9484,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:Flow Cyt (Intra), WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purity-Tissue culture supernatant, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The protein OTOP2 also known as Otopetrin 2 is involved in proton channel activity. It has an approximate molecular mass of 70 kDa. OTOP2 expresses in various tissues including the vestibular system and other sensory organs. Its role involves contributing to chemical gradients helping with cellular processes within these systems. This expression pattern points to its relevance in sensory functions mainly in maintaining balance and spatial orientation.
Biological function summary
OTOP2 influences ion balance in cells. This protein participates in cellular activities by modulating pH and ionic concentrations. OTOP2 often functions on its own without being part of larger protein complexes to achieve its regulatory roles. Its activity ensures cells maintain an environment that supports normal cellular operations and signaling particularly in response to external stimuli.
Pathways
OTOP2 plays a role in ion transport and sensory perception pathways. It aligns with key proteins involved in sensory signaling such as OTOP1 and OTOP3 which participate in similar sensory activities. This association indicates that OTOP2 functions in the contribution to sensory signal transduction. The involvement in these pathways highlights its importance in the body's response to sensory input and environmental changes.
OTOP2 connects to balance disorders like vestibular dysfunctions. Such conditions are due to the malfunction of sensory signaling related to balance. Proteins such as OTOP1 are similarly linked in these disorders emphasizing their collective importance in vestibular health. Additionally understanding how OTOP2 works can inform research into improved treatments for these conditions.