Abcam, ab192609, Anti-NLP1 antibody [EPR16545]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal NLP1 antibody. Suitable for IP, WB, ICC/IF, IHC-P and reacts with Human, Rat, Mouse samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR16545,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:WB, IHC-P, IP, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb
patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The NLP1 protein also known as nlp1 or nuclear localized protein 1 is a significant component in cellular processes. It has a molecular weight of approximately 25 kDa. Expression of NLP1 occurs mainly in the nucleus where it performs important tasks at the molecular level. It participates in various cellular functions by interacting with different molecules within the cell. The proper functioning and localization of NLP1 in the nucleus are important for its role in maintaining cellular integrity and response.
Biological function summary
This protein influences gene expression regulation by being part of transcriptional complexes. It interacts with other nuclear proteins to mediate the transcription of specific genes. Participation of NLP1 in these complexes allows it to influence cellular growth and differentiation processes. By controlling these functions NLP1 plays a significant part in the cellular response to external stressors indicating its role in adaptive cellular mechanisms.
Pathways
NLP1 integrates into transcriptional regulation pathways and cell cycle control pathways. In these pathways NLP1 closely interacts with proteins like cyclin-dependent kinases (CDKs) to affect the progression of the cell cycle. This interaction helps regulate important phases in the cell cycle and ensures that cells divide correctly. The involvement of NLP1 in these pathways is notable for maintaining normal cellular function and response.
NLP1 shows associations with cancer and neurological disorders. In cancer the dysregulation of NLP1 along with aberrant CDK activity can lead to unchecked cell proliferation. In neurological disorders altered gene expression caused by dysfunctional NLP1 activity can result in disrupted neural processes. These connections highlight the potential of NLP1 as a target for therapeutic interventions seeking to prevent or treat these conditions.