Abcam, ab20556, Anti-Bacillus cereus antibody

Size: 100µL
Rabbit Polyclonal Bacillus cereus antibody. Suitable for ICC/IF and reacts with Bacillus cereus, Bacillus subtilis samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Bacillus cereus protein.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Bacillus subtilis, Bacillus cereus,
Applications:ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:Reacts with spores and vegetative cells of Bacillus cereus and Bacillus subtilis. Antiserum is unabsorbed and may cross-react with other Bacillus species.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-Preservative: 0.1% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Bacillus cereus often referred to as B. cereus is a Gram-positive rod-shaped bacterium found in soil and the gastrointestinal tracts of some insects. It has a mass ranging between 3.1 and 5.2 megadaltons and thrives in a variety of environments due to its facultative anaerobic metabolism. B. cereus expresses various proteins that facilitate its survival and pathogenicity including enterotoxins responsible for food poisoning. These proteins are highly expressed in contaminated foodstuffs which often results in foodborne illnesses.
Biological function summary
Bacillus cereus serves as a model organism for studying bacterial sporulation and genome plasticity. This bacterium forms spores under unfavorable conditions which play a central role in its lifecycle and persistence in the environment. The sporulation process involves the formation of complex multi-protein structures ensuring the organism's survival during nutrient limitation. Additionally B. cereus synthesizes hemolysins and phospholipases important for its virulence enabling it to disrupt host cell membranes and release nutrients.
Pathways
Bacillus cereus integrates into host-pathogen interaction networks and the global carbon cycle. It engages in the oxidative respiration pathway affecting intermediary metabolism by transforming organic matter in the soil into carbon dioxide. This bacterium exhibits hexose utilization via the Embden-Meyerhof-Parnas pathway and produces lactate and other metabolites relevant in energy production. Proteins such as NheA and HblC components of its enterotoxin complexes interact with cellular pathways to disrupt host cellular functions.
Bacillus cereus most prominently links to gastrointestinal illnesses and eye infections. Its enterotoxins mainly those encoded by the nheABC and hblABCD genes contribute to the development of food poisoning manifesting as diarrhea and vomiting. Additionally B. cereus can cause rare but severe ocular infections where toxins like hemolysin BL play a critical role in tissue destruction. NheA and HblC proteins which form these toxins act synergistically in disease progression emphasizing their importance in B. cereus-related pathologies.