Abcam, ab213656, Anti-Annexin A10/ANXA10 antibody [EPR19507]

Size: 100µL / 1mL
Rabbit Recombinant Monoclonal Annexin A10/ANXA10 antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples. Cited in 11 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR19507,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Annexin A10 (ANXA10) also known as Annexin-10 is a protein with a molecular weight of approximately 37 kDa. You can find its expression mainly in the cytoplasm of epithelial cells especially in the gastrointestinal tract and liver. ANXA10 belongs to the annexin family which is known for calcium-dependent phospholipid binding. Its unique N-terminal region differentiates it from other annexin family members and may confer specific functions in cellular processes.
Biological function summary
ANXA10 functions as a calcium-dependent phospholipid-binding protein that regulates cell proliferation and differentiation. Though not part of a larger protein complex it may interact with cytoplasmic or membrane-associated proteins to perform its functions. ANXA10 helps maintain cellular integrity and possibly plays a role in the development of certain tissue types.
Pathways
ANXA10 plays a role in the cellular mechanisms involving vesicle trafficking and signal transduction. This protein contributes to the phospholipid metabolism and Annexin mechanisms working with other annexin proteins to mediate intracellular events. ANXA10 shares pathway relations with proteins such as Annexin A1 and Annexin A2 which also influence cell growth and signaling pathways.
Researchers have associated ANXA10 with liver cancer and gastric cancer. Altered expression of ANXA10 could contribute to tumor development and progression in these cancers. Studies show potential links with proteins like Annexin A8 in gastric cancer which makes ANXA10 a critical target of interest in cancer diagnostics and therapeutic research.