Abcam, ab218109, CK869, Actin-related protein 2/3 (Arp2/3) complex inhibitor

Size: 10mg / 25mg
MW 394.3 Da, Purity >98%. Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization with bovine Arp2/3 complex (IC 50 = 11 μM) and inhibits the formation of actin filament comet tails by Listeria monocytogenes in infected SKOV3 cells (IC 50 = 7 μM). Does not inhibit budding or fission yeast Arp2/3 complexes.
Key facts
CAS number:388592-44-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:394.3 Da,
Molecular formula:C17H16BrNO3S,
PubChem:3574452,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:2-(3-Bromophenyl)-3-(2,4-dimethoxyphenyl)-4-thiazolidinone,
Biological description:Inhibitor of human and bovine actin-related protein 2/3 (Arp2/3) complex. Inhibits actin polymerization with bovine Arp2/3 complex (IC50 = 11 μM) and inhibits the formation of actin filament comet tails by Listeria monocytogenes in infected SKOV3 cells (IC50 = 7 μM) . Does not inhibit budding or fission yeast Arp2/3 complexes.,
Canonical smiles:COC1=CC(=C(C=C1)N2C(SCC2=O)C3=CC(=CC=C3)Br)OC,
InChi:InChI=1S/C17H16BrNO3S/c1-21-13-6-7-14(15(9-13)22-2)19-16(20)10-23-17(19)11-4-3-5-12(18)8-11/h3-9,17H,10H2,1-2H3,
InChiKey:MVWNPZYLNLATCH-UHFFFAOYSA-N,
IUPAC Name:2-(3-bromophenyl)-3-(2,4-dimethoxyphenyl)-1,3-thiazolidin-4-one

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store in the dark