Abcam, ab219469, Dinaciclib, cyclin-dependent kinase (CDK) inhibitor

Size: 5mg
MW 396.5 Da, Purity >98%. Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC 50 values are 3, 1, 1 and 4 nM respectively). Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC 50 = 4 nM).
Key facts
CAS number:779353-01-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:396.5 Da,
Molecular formula:C21H28N6O2,
PubChem:46926350,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:Dinaciclib,
Biological description:Novel, potent, selective cyclin-dependent kinase (CDK) inhibitor displaying selectivity for CDK1, CDK2, CDK5 and CDK9 (IC50 values are 3, 1, 1 and 4 nM respectively). Potent DNA replication inhibitor that blocks thymidine incorporation in A2780 ovarian cancer cells (IC50 = 4 nM).,
Canonical smiles:CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCCC4CCO,
Isomeric smiles:CCC1=C2N=C(C=C(N2N=C1)NCC3=C[N+](=CC=C3)[O-])N4CCCC[C@H]4CCO,
InChi:InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1,
InChiKey:PIMQWRZWLQKKBJ-SFHVURJKSA-N,
IUPAC Name:2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 9537 Dinaciclib. 9537-25 is the same size as the 25 mg size of ab219469.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions