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BRAND / VENDOR: Abcam

Abcam, ab223879, beta-Nicotinamide mononucleotide, Key NAD+ intermediate

CATALOG NUMBER: ab223879
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Product Description

Size: 25mg / 100mg / 250mg
MW 334.22 Da, Purity >98%. Product of the NAMPT reaction and a key intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD + ). Ameliorates glucose intolerance by restoring NAD + levels in high-fat diet (HFD)-induced T2D mice. Enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.
Key facts
CAS number:1094-61-7,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:334.22 Da,
Molecular formula:C11H15N2O8P,
PubChem:14180,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biochemical name:Nicotinamide mononucleotide,
Biological description:Product of the NAMPT reaction and a key intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Ameliorates glucose intolerance by restoring NAD+ levels in high-fat diet (HFD)-induced T2D mice. Enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation.,
Canonical smiles:C1=CC(=C[N+](=C1)C2C(C(C(O2)COP(=O)(O)[O-])O)O)C(=O)N,
Isomeric smiles:C1=CC(=C[N+](=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)[O-])O)O)C(=O)N,
InChi:InChI=1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1,
InChiKey:DAYLJWODMCOQEW-TURQNECASA-N,
IUPAC Name:[(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl hydrogen phosphate

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 2733 β-Nicotinamide mononucleotide. 2733-250 is the same size as the 250 mg size of ab223879.
Protect from air and moisture.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions


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Collaboration

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