Abcam, ab227680, Anti-SOX10 antibody [SP267]

Size: 100µL / 500µL / 1mL
Anti-SOX10 antibody [SP267] (ab227680) is a rabbit monoclonal antibody detecting SOX10 in Western Blot, Flow Cytometry (Intra), Flow Cytometry, IHC-P, ICC/IF . Suitable for Human, Mouse, Rat . - Biophysical QC for unrivalled batch-batch consistency - Over 10 publications
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:SP267,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Rat, Human,
Applications:ICC/IF, IHC-FoFr, IHC-P, WB, Flow Cyt (Intra)See reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Anti-SOX10 antibody [SP267] (ab227680) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-FoFr IHC-P and WB.
Abcam's high quality manufacturing and validation processes ensure Anti-SOX10 antibody [SP267] (ab227680) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility.
Anti-SOX10 antibody [SP267] (ab227680) has 5 independent reviews from customers.
Anti-SOX10 antibody [SP267] (ab227680) specifically detects SOX10 (UniProt ID: P56693; Molecular weight: 50kDa) and is sold in 100 µL, 500 µL and 1 mL selling sizes.
Conjugation-ready, carrier free format available for antibody clone SP267 - ab239752.
Antibody clone SP267 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor
488, Alexa Fluor
647, PE, Alexa Fluor
555, APC, Alexa Fluor
594, Alexa Fluor
ab270150
ab270151
ab270152
ab307763
ab310845
ab311668
ab313897
Anti-SOX10 antibody [SP267] (ab227680) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC).
SOX10 is a crucial transcription factor in neuro research, particularly for its role in the development and differentiation of neural crest cells and glial cells. It is essential for the formation of Schwann cells and oligodendrocytes, which are vital for myelination in the peripheral and central nervous systems. Researchers use SOX10 to study neural crest cell fate, myelination processes and related disorders, making it vital for understanding neurodevelopmental diseases and demyelinating conditions.Additionally, SOX10 plays a significant role in melanoma, an aggressive form of skin cancer. It is highly expressed in melanoma cells and is essential for their proliferation and survival. Altered SOX10 expression can influence melanoma progression and drug resistance, making it a critical target for understanding and potentially treating melanoma.
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.1% Sodium azideConstituents: PBS, 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle