Abcam, ab236383, Anti-FAM131C antibody [OTI6E2]

Size: 100µL
Mouse Monoclonal FAM131C antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FAM131C.
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:OTI6E2,
Isotype:IgG1,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Full Length Protein corresponding to Human FAM131C.Q96AQ9

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Purification notes-Purified from cell culture supernatant., Storage buffer-pH: 7.3Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The FAM131C protein sometimes referred to simply as a member of the FAM131 protein family shows interesting mechanical functions. With a molecular mass of approximately 30 kDa the FAM131C protein can be detected in several tissues although its expression is particularly noted in the brain and certain immune cells. It often associates with cellular processes that are vital to its mechanical roles.
Biological function summary
The FAM131C protein plays important roles in regulating cellular signaling and communication. As a part of various multiprotein complexes FAM131C interacts with other proteins to modulate immune responses and may influence cell proliferation. This protein shows potential involvement in the modulation of pathways related to cell survival and apoptosis.
Pathways
FAM131C has clear involvement in intracellular signaling pathways. It is associated with the MAPK pathway which is integral to various cellular processes like proliferation and differentiation. FAM131C interacts with proteins such as ERK and MEK contributing to signal transduction mechanisms. Additionally its roles in immune signaling pathways show significant interaction with molecules like NF-kB.
FAM131C has been linked to neurological conditions and certain immunological disorders. Its involvement in processes related to brain function and immune regulation suggests a connection to diseases like Alzheimer's disease and autoimmunity. Further interaction studies highlight connections with proteins such as tau in the context of neurological conditions providing insights into potential therapeutic targets.