Abcam, ab238926, Anti-RPS10 antibody [EPR8545] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal RPS10 antibody. Carrier free. Suitable for WB, ICC/IF, Flow Cyt (Intra), IHC-P and reacts with Mouse, Rat, Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR8545,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Rat, Human,
Applications:Flow Cyt (Intra), WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab238926 is the carrier-free version of
ab151550
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
RPS10 also known as 40S ribosomal protein S10 is a component of the small ribosomal subunit essential for protein synthesis. It weighs approximately 18.7 kDa. The protein is expressed in various tissues including the liver kidney and brain. Its primary role involves participating in the assembly and function of ribosomes by interacting with rRNA and supporting the translation of mRNA into amino acids.
Biological function summary
RPS10 contributes to the formation and stability of the ribosomal 40S subunit. It works as part of the ribosome complex important for initiating and propelling protein synthesis. This ribosomal complex performs a central role in cellular growth and proliferation as it aids in assembling polypeptide chains that proteins need for diverse cellular processes. By doing so it supports a wide range of physiological functions.
Pathways
RPS10 contributes to protein synthesis through the translational initiation and elongation pathways. Its participation supports the accurate decoding and synthesis of proteins which are critical to cellular metabolism and growth. RPS10 interacts with other ribosomal proteins such as RPS12 and RPS14 to maintain these pathways' function and efficiency helping regulate cellular homeostasis and response to environmental stimuli.
RPS10 mutations can link to Diamond-Blackfan Anemia a condition marked by failed red blood cell production impacting patient health. Moreover aberrations in RPS10 link to various cancers such as breast cancer due to its role in protein synthesis and cell growth. RPS10 interacts with proteins like RPL5 another ribosomal protein within these disease contexts suggesting a broader contribution of ribosomal dysfunction in disease pathogenesis.