Abcam, ab249487, Anti-MYO1F antibody [EPR11611] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal MYO1F antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR11611,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab249487 is the carrier-free version of
ab169535
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
MYO1F also known as Myosin IF is a motor protein that functions mechanically as part of the class I myosin family. It has a molecular mass of approximately 129 kDa. MYO1F expresses in various tissues with high levels in immune cells like macrophages and lymphocytes. It carries out cellular functions through its ATPase activity enabling it to interact with actin filaments and facilitate cellular movement and membrane tension.
Biological function summary
MYO1F plays a role in processes that involve cell movement and organization of the cortical actin cytoskeleton. It does not typically function as part of a complex but actively associates with actin to effect changes in cell shape and motility. Its activity is important for immune cell function contributing to events like phagocytosis and cell signaling.
Pathways
MYO1F integrates into cellular processes such as the actin cytoskeleton regulation and intracellular signaling pathways. It is especially significant in immune-related pathways where it interacts with proteins like actin and other myosin isoforms to support cellular dynamics. Its involvement in these pathways highlights its role in modulating responses to immune challenges.
MYO1F associates with immune-related conditions such as immunodeficiency and inflammatory diseases. Alterations in MYO1F expression or function can disrupt immune cell activities linking it to disorders like systemic lupus erythematosus and chronic inflammatory pseudotumor. In these contexts MYO1F impacts disease processes alongside proteins like talin and vinculin affecting cell adhesion and signaling mechanisms.