Abcam, ab250272, Anti-RBMX2 antibody [EPR14394] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal RBMX2 antibody. Carrier free. Suitable for ICC/IF, WB, IHC-P and reacts with Human, Mouse samples. Cited in 2 publications.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR14394,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Human,
Applications:ICC/IF, IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab250272 is the carrier-free version of
ab180940
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
RBMX2 also known as RNA-binding motif protein X-linked 2 (RBMY2 or hnRNP G-T) is a protein that binds to RNA to help regulate gene expression. This protein weighs approximately 40 kDa and is located primarily within the nucleus of cells. RBMX2 shows expression in various tissues with noticeable levels in testis tissue and to some extent in other organs suggesting a role in specific cellular processes.
Biological function summary
RNA-binding motif proteins like RBMX2 engage in RNA splicing processing and transport thereby influencing RNA metabolism. RBMX2 may be a part of ribonucleoprotein complexes that modulate mRNA processing events. These complexes maintain RNA stability and facilitate efficient gene expression impacting cell differentiation and proliferation.
Pathways
The RBMX2 protein influences RNA processing pathways. It interacts with other RNA-binding proteins such as DAZL and hnRNPA2/B1 in these pathways. These interactions highlight its involvement in post-transcriptional regulatory networks which control the proper maturation and trafficking of mRNAs essential for cellular functions.
RBMX2's aberrant expression can relate to testicular dysgenesis and reproductive issues. Alterations in RBMX2 functionality have connections with infertility particularly involving the DAZ gene family critical for spermatogenesis. Disruptions in these pathways might lead to improper RNA processing contributing to developmental defects and infertility-related syndromes.