Abcam, ab250712, Anti-Olfactory Marker Protein/OMP antibody [EPR19190] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal Olfactory Marker Protein/OMP antibody. Carrier free. Suitable for IP, WB, IHC-Fr, IHC-P and reacts with Mouse, Rat samples.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR19190,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Mouse, Rat,
Applications:IHC-P, IHC-Fr, IP, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab250712 is the carrier-free version of
ab183947
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Olfactory Marker Protein (OMP) sometimes referred to as OMP protein or marker protein plays a significant role in the olfactory system. With a molecular mass of approximately 19 kDa OMP is primarily expressed in mature olfactory sensory neurons within the olfactory epithelium. These neurons play an important role in detecting and transmitting odorant signals to the brain. The expression of OMP is often used as an indicator of functional olfactory neurons.
Biological function summary
OMP participates in enhancing the signal transduction process of olfactory sensory neurons. It acts as a modulator in the cascade that follows the initial odorant detection ensuring the proper response and adaptation of the neurons to smells. OMP is not part of any major protein complex but it influences the activity of other signaling molecules within the neuron affecting how signals are shaped and perceived.
Pathways
Studies show that OMP is involved in the olfactory signal transduction pathway. This pathway includes interactions with other proteins like cyclic nucleotide-gated channels which are critical for converting chemical signals from odorants into electrical signals in neurons. By modulating these pathways OMP contributes to the accurate representation of olfactory information ultimately affecting the brain's sensory perception.
Changes in OMP expression can relate to conditions impacting the sense of smell such as anosmia which is the loss of olfactory function. Connections exist between OMP and other proteins involved in neurodegenerative diseases like Alzheimer's where olfactory dysfunction is an early symptom. Although not the sole factor OMP's presence in these conditions offers a biomarker potential for early diagnosis or understanding progression.