Abcam, ab251069, Anti-REEP2 antibody [EPR16080] - BSA and Azide free

Size: 100µg / 1mg
Rabbit Recombinant Monoclonal REEP2 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR16080,
Isotype:IgG,
Carrier free:Yes,
Reacts with:Human,
Applications:WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
ab251069 is the carrier-free version of
ab191410
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies
Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.
Use our
conjugation kits
for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
Compatibility
This product is compatible with the Maxpar
Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar
is a trademark of Fluidigm Canada Inc.

Properties and Storage Information:
Form-Liquid, Storage buffer-pH: 7.2 - 7.4Constituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Do Not Freeze

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
REEP2 also known as Receptor Expression Enhancing Protein 2 plays an important role in shaping membrane structures such as the endoplasmic reticulum. It has a molecular mass of approximately 24 kDa. This protein is expressed in various tissues including the central nervous system and peripheral tissues. REEP2 assists in modulating the surface expression of receptors facilitating their proper localization within the cell.
Biological function summary
Proteins like REEP2 participate in the formation of tubular endoplasmic reticulum structures. It is often part of a complex with other proteins like the Atlastin family which contributes to the shaping and remodeling of cellular membranes. REEP2 helps in maintaining cellular processes that depend on intact membrane architecture supporting the dynamic nature of the cellular environment.
Pathways
Cellular processes involving endoplasmic reticulum development highlight the function of proteins such as REEP2. It is intricately involved in the endoplasmic reticulum network pathways. These pathways often include interactions with proteins such as Reticulon which also contribute to membrane structure. By participating in these pathways REEP2 supports intracellular processes necessary for maintaining cellular homeostasis.
Proteins like REEP2 have connections to neurological conditions such as hereditary spastic paraplegia (HSP). Mutations in REEP2 can lead to the degeneration of nerves causing motility issues. Additionally its interaction with Spastin has been associated with severe phenotypes of HSP highlighting its critical role in maintaining neural integrity. Understanding REEP2's function and relationship to disorders offers potential avenues for therapeutic exploration.