Abcam, ab254452, Defactinib, FAK inhibitor

Size: 5mg / 25mg
MW 510.5 Da, Purity >98%. Potent FAK inhibitor. Prevents tumor invasion and dissemination. Preferentially targets cancer stem cells in mouse xenograft models. Orally bioavailable.
Key facts
CAS number:1073154-85-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:510.5 Da,
Molecular formula:C20H21F3N8O3S,
PubChem:25117126,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biochemical name:Defactinib,
Biological description:Potent FAK inhibitor. Prevents tumor invasion and dissemination. Preferentially targets cancer stem cells in mouse xenograft models. Orally bioavailable.,
Canonical smiles:CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F,
InChi:InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30),
InChiKey:FWLMVFUGMHIOAA-UHFFFAOYSA-N,
IUPAC Name:N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide

Product details:
Solutions in DMSO may be stored at -20°C for up to 3 months.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions