Abcam, ab273533, CCT128930

Size: 5mg / 10mg / 50mg
MW 341.8 Da, Purity 98%. Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.
Key facts
CAS number:885499-61-6,
Purity:98%,
Form:SolidSee storage information,
Molecular weight:341.8 Da,
Molecular formula:C18H20ClN5,
PubChem:17751819,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM,
Biochemical name:4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine,
Biological description:Potent and selective AKT2 inhibitor (IC50= 6 nM) with selectivity greater than 28-fold and 20-fold over PKA kinase (IC50= 168 nM) and p70S6K (IC50= 120 nM), respectively.,
Canonical smiles:C1CN(CCC1(CC2=CC=C(C=C2)Cl)N)C3=NC=NC4=C3C=CN4,
InChi:InChI=1S/C18H20ClN5/c19-14-3-1-13(2-4-14)11-18(20)6-9-24(10-7-18)17-15-5-8-21-16(15)22-12-23-17/h1-5,8,12H,6-7,9-11,20H2,(H,21,22,23),
InChiKey:RZIDZIGAXXNODG-UHFFFAOYSA-N,
IUPAC Name:4-[(4-chlorophenyl)methyl]-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine

Product details:
For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while.

Properties and Storage Information:
Shipped at conditions-Blue Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C