Abcam, ab273892, 5-Fluorouridine 5'-O-β-D-galactopyranoside

Size: 5mg
MW 424.33 Da, Purity 98%. Potent anti-metabolite. Acts via thymidylate synthetase inhibition or incorporation into RNA *in vivo*. Analog of 5-fluorouridine. Has galactose conjugated to the active site. Enzymatic or chemical hydrolysis of the galactoside group releases the active anti-metabolite. Useful for cell selection through lacZ specific release of 5-fluorouridine in recombinant cells or tissues.
Key facts
CAS number:149965-92-4,
Purity:98%,
Form:SolidSee storage information,
Molecular weight:424.33 Da,
Molecular formula:C15H21FN2O11,
PubChem:9867013,
Nature:Synthetic,
Solubility:Soluble in DMSOSoluble in water,
Biochemical name:5'-O-beta-D-Galactosyl-5-fluorouridine,
Biological description:Potent anti-metabolite. Acts via thymidylate synthetase inhibition or incorporation into RNA *in vivo*. Analog of 5-fluorouridine. Has galactose conjugated to the active site. Enzymatic or chemical hydrolysis of the galactoside group releases the active anti-metabolite. Useful for cell selection through lacZ specific release of 5-fluorouridine in recombinant cells or tissues.,
Canonical smiles:C1=C(C(=O)NC(=O)N1C2C(C(C(O2)COC3C(C(C(C(O3)CO)O)O)O)O)O)F,
Isomeric smiles:C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)O)O)O)F,
InChi:InChI=1S/C15H21FN2O11/c16-4-1-18(15(26)17-12(4)25)13-10(23)8(21)6(28-13)3-27-14-11(24)9(22)7(20)5(2-19)29-14/h1,5-11,13-14,19-24H,2-3H2,(H,17,25,26)/t5-,6-,7+,8-,9+,10-,11-,13-,14-/m1/s1,
InChiKey:BTPARJRXLUUYJW-FQKYAJAOSA-N,
IUPAC Name:1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxolan-2-yl]-5-fluoropyrimidine-2,4-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions