Abcam, ab278073, LDN 193189 dihydrochloride

Size: 5mg / 25mg
MW 479.4 Da, Purity >99%. Potent and selective inhibitor of ALK2 (IC 50 = 5 nM) and ALK3 (IC 50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.
Key facts
CAS number:1435934-00-1,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:479.4 Da,
Molecular formula:C25H24Cl2N6,
PubChem:91900717,
Nature:Synthetic,
Solubility:Soluble in water to 10 mM,
Biochemical name:LDN 193189 dihydrochloride,
Biological description:Potent and selective inhibitor of ALK2 (IC50 = 5 nM) and ALK3 (IC50 = 30 nM), thereby inhibiting SMAD1/5/8 phosphorylation.,
Canonical smiles:C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl,
InChi:InChI=1S/C25H22N6.2ClH/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30;;/h1-10,15-17,26H,11-14H2;2*1H,
InChiKey:CMQXLLAILGGLRV-UHFFFAOYSA-N,
IUPAC Name:4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline;dihydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions