Abcam, ab308289, Anti-Porcine circovirus 2-Capsid protein antibody [EPR28077-77]

Size: 10µL-TRIAL / 20µL / 100µL / 1mL
Rabbit Recombinant Monoclonal CAPSD antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Transfected cell lysate - Porcine circovirus 2, Transfected cell line - Porcine circovirus 2 samples.
Key facts
Host species:Rabbit,
Clonality:Monoclonal,
Clone number:EPR28077-77,
Isotype:IgG,
Carrier free:No,
Reacts with:Porcine circovirus 2,
Applications:IHC-P, ICC/IF, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.

Product details:
Patented technology
Our RabMAb
technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to
RabMAb® patents
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production
For more information, read more on
recombinant antibodies

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.2 - 7.4Preservative: 0.01% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The porcine circovirus capsid protein also known as the PCV2 capsid is a primary structural protein integral to the assembly of the virus's protective shell. This protein has a molecular mass of approximately 25 kDa. It is expressed in infected host cells where it plays a significant role in the packaging and protection of the viral genome. The capsid protein is essential for the virion's entry into host cells and subsequent infection cycle.
Biological function summary
The porcine circovirus capsid protein enables the virus to persist in swine hosts by facilitating the immune evasion mechanisms. It forms part of the complete virion structure contributing to the virus's stability in the environment and subsequent transmission between animals. The protein does not alone form a complex but interacts closely with viral genomic elements and host cell machinery to carry out its biological role efficiently.
Pathways
The capsid protein of porcine circovirus integrates into viral replication and immune modulation pathways. It interacts with host signaling proteins that regulate antiviral responses potentially interfering with pathways such as the interferon signaling pathway. These interactions help the virus evade host immunity and support the viral lifecycle within infected swine leading to persistent infection.
Porcine circovirus capsid protein has direct links to porcine circovirus-associated diseases (PCVAD). These include post-weaning multisystemic wasting syndrome (PMWS) which severely impacts swine health and productivity. The capsid protein interacts with host cellular proteins influencing disease outcomes and pathology. Continued research into capsid-host interactions might offer insights into therapeutic interventions or vaccine development strategies against PCV2-associated diseases.