Abcam, ab53066, Anti-Fibroblast activation protein, alpha antibody

Size: 100µg
Anti-Fibroblast activation protein, alpha antibody (ab53066) is a rabbit polyclonal antibody detecting Fibroblast activation protein, alpha in Western Blot, IHC-P . Suitable for Human . - Over 130 publications - Trusted since 2007
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human FAP. The exact immunogen used to generate this antibody is proprietary information.Q12884,
Specificity:ab53066 detects endogenous levels of total Fibroblast activation protein, alpha. Please note the immunogen used to produce this product has 92% homology with Mouse DPPIV/CD26.

Product details:
Anti-Fibroblast activation protein, alpha (FAP) antibody (ab53066) is a rabbit polyclonal antibody and is validated for use in IHC-P, WB in human, mouse, rabbit samples.
Anti-Fibroblast activation protein, alpha antibody (ab53066) has been cited over 134 times in peer reviewed journals and is trusted by the scientific community.
Abcam's high quality validation processes ensure Anti-Fibroblast activation protein, alpha antibody (ab53066) has high sensitivity and specificity.
Anti-Fibroblast activation protein, alpha antibody (ab53066) has 13 independent reviews from customers.
Anti-Fibroblast activation protein, alpha antibody (ab53066) specifically detects Fibroblast activation protein, alpha (UniProt ID: Q12884; Molecular weight: 88kDa) and is sold in 100 µg selling sizes.
Fibroblast activation protein (FAP) is a type II transmembrane serine protease predominantly expressed in cancer-associated fibroblasts (CAFs) within the tumor microenvironment. Fibroblast activation protein (FAP) plays a crucial role in remodeling the extracellular matrix, promoting tumor growth, invasion, and metastasis. It is minimally expressed in normal tissues but significantly upregulated in various cancers, making it a potential biomarker for malignancy.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Purification notes-ab53066 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen., Storage buffer-pH: 7Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Stable for 12 months at -20°C