Abcam, ab54210, Anti-CDKN2A/p16INK4a antibody [2D9A12]

Size: 100µL
Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) is a mouse monoclonal antibody detecting CDKN2A/p16INK4a in Flow Cytometry, IHC-P . Suitable for Human, Rat . - Over 140 publications - Trusted since 2007
Key facts
Host species:Mouse,
Clonality:Monoclonal,
Clone number:2D9A12,
Isotype:IgG2b,
Carrier free:No,
Reacts with:Rat, Human,
Applications:Flow Cyt, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human CDKN2A. The exact immunogen used to generate this antibody is proprietary information.P42771

Product details:
Product Specifications
Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) is a mouse monoclonal antibody and is validated for use in Flow Cyt, IHC-P in human, rat samples.
Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) specifically detects CDKN2A/p16INK4a (UniProt ID: P42771; Molecular weight: 17kDa) and is sold in 100 µL selling sizes.
Quality and Validation
Abcam's high quality validation processes ensure Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) has high sensitivity and specificity.
Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) has been cited over 142 times in peer reviewed journals and is trusted by the scientific community.
Anti-CDKN2A/p16INK4a antibody [2D9A12] (ab54210) has 18 independent reviews from customers.
Target Information
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a crucial tumor suppressor gene located on chromosome 9p211. It encodes two proteins, p16INK4a and p14ARF, both of which play significant roles in regulating the cell cycle. p16INK4a inhibits cyclin-dependent kinases 4 and 6 (CDK4 and CDK6), preventing the progression from the G1 to S phase of the cell cycle. This inhibition is vital for controlling cell proliferation and preventing tumor growth. Mutations or deletions in CDKN2A are frequently associated with various cancers, including melanoma, pancreatic cancer, and head and neck squamous cell carcinoma.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Purification notes-Purified from tissue culture supernatant., Storage buffer-Preservative: 0.03% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle