Abcam, ab68540, Anti-Enterococcus antibody

Size: 500µL
Rabbit Polyclonal Enterococcus antibody. Suitable for ICC, ELISA and reacts with Enterococcus faecium samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Enterococcus protein.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Enterococcus faecium,
Applications:ELISA, ICCSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:The exact immunogen used to generate this antibody is proprietary information.,
Specificity:This antibody reacts with Enterococcus in bacterial and infected tissue samples.

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification, Storage buffer-pH: 7.2Preservative: 0.1% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Enterococcus is a gram-positive bacterium sometimes referred to as enterococci and it primarily includes the species Enterococcus faecalis and Enterococcus faecium. These bacteria typically weigh around 1.6 femtograms per cell. They inhabit the gastrointestinal tracts of humans and animals. Enterococci can survive harsh conditions such as high salt concentrations and acidic environments and they display significant resilience to many antibiotics.
Biological function summary
Enterococci play a role in the intestinal microbiome helping maintain gut health. They are part of a larger community of microbes working together to decompose complex carbohydrates and synthesize vitamins. Enterococci can act as opportunistic pathogens especially in weakened immune systems potentially disrupting normal physiological functions. Under certain conditions they may form biofilms which are microbial communities that enhance their survival and resistance to antibiotics.
Pathways
Enterococci involve themselves in processes related to antibiotic resistance and biofilm formation. The vancomycin-resistant Enterococcus (VRE) pathway is significant where enterococci acquire resistance genes that alter the peptidoglycan synthesis in their cell wall. They interact with proteins such as D-Ala-D-Ala ligases and VanA-type ligases which play roles in maintaining this resistance and modifying cellular structures to evade antibiotic action.
Enterococci relate to nosocomial infections and urinary tract infections (UTIs). As opportunistic pathogens they often cause infections in hospital settings especially when the patient has compromised immune defenses. In cases of UTIs enterococci interact with proteins involved in immune response and inflammation such as interleukin-6. Their capacity to form biofilms complicates treatment as these biofilms shield the bacteria from both the host's immune system and administered antibiotics.