Abcam, ab79960, Anti-Pig Albumin antibody

Size: 150µg
Rabbit Polyclonal Albumin antibody. Suitable for ELISA, WB, IHC-P, RIA, EIA and reacts with Pig samples. Cited in 9 publications. Immunogen corresponding to Native Full Length Protein corresponding to Pig Albumin.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Pig,
Applications:ELISA, RIA, EIA, WB, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Native Full Length Protein corresponding to Pig Albumin.P08835

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein G, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, 50% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
Pig Albumin also known as serum albumin is a large protein with a molecular mass of approximately 67 kDa. This globular protein is mostly found in blood plasma where it plays a critical role in maintaining oncotic pressure and transporting different molecules. It is synthesized mainly in the liver and due to its high abundance it is an important component in regulating fluid balance throughout the body.
Biological function summary
Albumin plays several roles beyond transport. It has binding capabilities that allow it to carry hormones fatty acids and drugs acting as a carrier for a wide variety of substances. Albumin is not considered part of a complex; rather it functions independently in the bloodstream. Its ability to bind a diverse range of ligands comes from multiple binding sites making it a versatile protein in physiological processes.
Pathways
Albumin participates in the Renin-Angiotensin-Aldosterone System (RAAS) and other pathways linked to fluid balance and distribution. In the RAAS albumin helps in maintaining blood volume and pressure. It also interacts with proteins such as angiotensinogen contributing to vascular homeostasis. This involvement helps the body respond to changes in blood pressure and volume vital for cardiovascular health.
Albumin levels are markers in conditions like kidney disease and liver cirrhosis. Hypoalbuminemia a condition of low albumin levels often indicates issues with one of these organs. It is linked with modified levels of other plasma proteins like globulins and fibrinogen during disease states. Monitoring albumin provides important insights into the severity and progression of these conditions making it a critical protein in clinical diagnostics.