Agilent, 5190-2416, Agilent Bio MAb, NP10, 4.6 x 50 mm, PEEK

Agilent Bio MAb, NP10, 4.6 x 50 mm, PEEK. This HPLC column has a densely packed weak cation exchange layer designed for monoclonal antibody separations. PEEK hardware enables this column to couple with bio-compatible or bio-inert LC systems.

Specifications:
Brand: Agilent Bio MAb
Hardware: PEEK
Inner Diameter (ID): 4.6 mm
LC Platform: BioInert
Length: 50 mm
Maximum Temperature: 80 °C
Part Number Application Domain: Biopharma
Part Number Application: Charge Variant AnalysisPeptidesProteinsmAbs
Particle Size: 10 µm
Particle Type: Non-porous
Phase: WCX
Pressure Rating: 275 bar
Separation Mode: Ion Exchange (IEX)
Shipping Solvent: Phosphate Buffer
Technique: LC
UNSPSC Code: 41115711
pH Range: 2-12

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The Agilent Bio MAb NP10 column, measuring 4.6 x 50 mm and constructed with PEEK hardware, is designed for the high-resolution analysis and characterization of monoclonal antibodies and related biologics using size exclusion chromatography. Its NP10 stationary phase enables exceptional separation of proteins and aggregates, making it an essential tool for assessing product purity, stability, and aggregation in biopharmaceutical research and quality control laboratories. The PEEK construction ensures biocompatibility, minimizing sample interaction and providing durability for routine analytical workflows.

This column is ideal for analytical workflows investigating mAbs, antibody fragments, or other large biomolecules, supporting tasks such as aggregate quantification, stability indication, and comparative studies across formulations. Compatible with a wide range of Agilent 1200 Infinity and 1260 Infinity II LC systems, as well as other industry-standard UHPLC instruments, its robust design supports repeatable and reliable data generation.

For optimal performance in regulated biotherapeutic development and manufacturing environments, this column pairs well with Agilent’s full portfolio of Bio MAb column chemistries and supplementary SEC columns. It is recommended for scientists and researchers requiring high-efficiency, reproducible analysis of protein pharmaceuticals under mild, nondenaturing conditions.