Agilent, 797775-944, AdvanceBio RP-mAb Diphenyl, 2.1 x 75 mm, 3.5 µm

AdvanceBio RP-mAb Diphenyl, 2.1 x 75 mm, 3.5 µm. A reversed-phase diphenyl HPLC column with superficially porous particles and a wide (450 Å) pore size designed for mAbs and other larger proteins when alternate selectivity is needed or preferred.

Specifications:
Brand: AdvanceBio RP mAb Diphenyl
Hardware: SS
Inner Diameter (ID): 2.1 mm
LC Platform: Stainless Steel
Length: 75 mm
Maximum Temperature: 90 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)Proteins
Particle Size: 3.5 µm
Particle Type: Superficially Porous
Phase: Diphenyl
Pore Size: 450 Å
Pressure Rating: 600 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-8

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The Agilent AdvanceBio RP-mAb Diphenyl column is engineered for high-resolution reversed-phase separations of monoclonal antibodies and related biotherapeutics. Featuring a 2.1 x 75 mm dimension and 3.5 µm particle size, this column leverages a unique diphenyl bonded phase to deliver excellent selectivity for both intact and subunit analysis. Its robust design ensures consistent performance for critical quality assessment, including purity analysis, aggregation studies, and product heterogeneity profiling in both research and biopharmaceutical quality control laboratories.

This column is optimized for use with Agilent liquid chromatography systems, such as the 1260 Infinity II and 1290 Infinity LC series, as well as compatible with a wide range of UHPLC and HPLC platforms commonly found in analytical labs. AdvanceBio RP-mAb Diphenyl columns are particularly suited for detailed characterization of mAbs, antibody-drug conjugates, and related proteins under denaturing and non-denaturing conditions. When paired with Agilent AdvanceBio family sample preparation solutions and detectors, users achieve reliable, reproducible results with minimal method development. This column supports regulated workflows and helps streamline analytical processes in development and manufacturing environments, ensuring confident decision-making in biotherapeutic analysis.