Agilent, PL1212-4800, PLRP-S 300Å, 25 x 25 mm, 8 µm, guard (1/16 in)

PLRP-S 300Å, 25 x 25 mm, 8 µm, guard (1/16 in). Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Guard Column: Yes
Hardware: SS
Inner Diameter (ID): 25 mm
LC Platform: Stainless Steel
Length: 25 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: PeptidesPreparative HPLC Columns & Bulk MediaProteins
Particle Size: 8 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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The PLRP-S 300Å, 25 x 25 mm, 8 µm guard cartridge offers reliable protection for analytical HPLC columns by filtering particulates and preventing sample contamination. Designed for use in reversed-phase chromatography, it utilizes a highly cross-linked polystyrene-divinylbenzene (PS-DVB) polymeric stationary phase with 300 angstrom pores and 8 micron particle size, providing robust chemical and physical stability under a variety of mobile phase conditions. This makes it suitable for demanding applications such as protein and peptide separations, biopolymers, and hydrophobic molecules. The guard cartridge preserves the lifespan and performance of the primary analytical column by intercepting contaminants before they reach the main bed. Engineered for compatibility with 1/16-inch standard HPLC fittings, it integrates easily with a wide range of Agilent LC systems as well as other major liquid chromatography platforms. The guard is highly recommended for workflows employing PLRP-S analytical columns, ensuring reliable and reproducible chromatographic performance in pharmaceutical, biotechnology, and academic research laboratories. Utilizing this guard cartridge extends maintenance intervals and reduces operational downtime, supporting high-throughput environments and routine method development for biotherapeutic and advanced analytical studies.