Agilent, PL1512-1300, PLRP-S 100Å, 4.6 x 50 mm, 3 µm

PLRP-S 100Å, 4.6 x 50 mm, 3 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 50 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 3 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 100 Å
Pressure Rating: 275 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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This high-performance reversed-phase chromatography column features a 100 angstrom pore size and 3 micron particle size, housed in a 4.6 x 50 millimeter dimension. Engineered for reliability and reproducibility, the column utilizes rigid, spherical polystyrene-divinylbenzene beads, ensuring minimal bleed and broad chemical compatibility. It is ideally suited for the separation and analysis of peptides, synthetic oligonucleotides, and small proteins, delivering sharp peak resolution even for challenging hydrophobic samples.

This product is compatible with a wide range of Agilent HPLC and UHPLC systems, as well as many other standard liquid chromatography platforms. Its robust design accommodates high temperature and pH ranges, providing flexibility for complex analytical and preparative workflows. This versatility makes it well-suited for pharmaceutical development, quality control, proteomics, and biotherapeutics characterization.

Researchers benefit from consistent batch-to-batch performance and extended column lifetime, supporting demanding applications such as peptide mapping, oligonucleotide purity assessment, and hydrophobic interaction studies. For complementary workflows, consider integrating with Agilent detectors, fraction collectors, and additional column chemistries tailored to specific analytes. Advanced sample loading capacity and durability make this column an excellent solution for both routine analysis and innovative research in life science laboratories.