Agilent, PL1512-5501, PLRP-S 300Å, 4.6 x 250 mm, 5 µm

PLRP-S 300Å, 4.6 x 250 mm, 5 µm. Reversed-phase HPLC column with fully porous PS/DVB particle support stable at elevated temperatures and a wide pH range(1-14). Available in range of particle and pore sizes for targeted applications

Specifications:
Brand: PLRP-S
Hardware: SS
Inner Diameter (ID): 4.6 mm
LC Platform: Stainless Steel
Length: 250 mm
Maximum Temperature: 200 °C
Part Number Application Domain: Biopharma
Part Number Application: Intact & Subunit AnalysisMonoclonal Antibodies (mABs)PeptidesProteins
Particle Size: 5 µm
Particle Type: Fully Porous
Phase: DVB
Pore Size: 300 Å
Pressure Rating: 207 bar
Separation Mode: Reversed Phase
Shipping Solvent: Acetonitrile/Water
Technique: LCLC & LC/MS
UNSPSC Code: 41115711
pH Range: 1-14

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Designed for high-performance liquid chromatography, this polymeric reversed-phase column features a 300 Angstrom pore size, 4.6 mm internal diameter, 250 mm length, and 5 micron particle size. Its robust hydrophobic polystyrene-divinylbenzene matrix ensures excellent chemical and pH stability across a wide pH range, making it an optimal choice for the analysis of large biomolecules such as peptides, oligonucleotides, and proteins. The large pore structure facilitates enhanced resolution and recovery of high-molecular-weight analytes, supporting critical workflows in biopharmaceutical development, proteomics, and peptide mapping.

This column delivers consistent retention times and reproducible results, even under demanding gradient or isocratic conditions. Its compatibility with most HPLC and UHPLC systems enables seamless integration into existing laboratory setups. Ideal for both quality control and research environments, it offers high loadability and minimal carryover, ensuring reliable quantitation and characterization.

Recommended for use with Agilent’s full range of LC instruments and mobile phase systems, this column can also be paired with related detection technologies such as mass spectrometry for advanced analytical requirements. Its durable construction provides extended column life, supporting rigorous daily operation for laboratories focused on biotherapeutics and complex biological samples.