Biolegend, 162804, PE anti-mouse UNC93B1 Antibody, 100μg

Unc93b1 is a 12 pass transmembrane protein highly conserved in the endoplasmic reticulum (ER). Unc93b1 plays a role in the transport of TLRs from the ER to the cell surface or endosomes where they can engage pathogens nucleotides and trigger signaling cascades. Mutations in the Unc93b1 gene have shown to cause susceptibility to some common infections (HSV hypersensitivity in humans, and mouse cytomegalovirus).
100μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse UNC93B1-transfectants
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: 0.2 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: ICFC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.03 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2888874 (BioLegend Cat. No. 162804)
Structure: 12 pass transmembrane protein
Antigen References: 1. Majer. et al. 2019. Nature. 575, 371–374 2. Pelka et al. 2018. Immunity. 48, 911–922 3. Huh et al. 2014. PNAS. 111, 7072–7077
Gene ID: 81622
UniProt: View information about UNC93B1 on UniProt.org
Clone: S19013C
Regulatory Status: RUO
Other Names: Unc-93 homolog B1, TLR signaling regulator
Isotype: Rat IgG2a, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.