Biolegend, 163004, FITC anti-mouse CD36 Antibody, 100μg

CD36 is a 85 kD glycoprotein, also known as FAT, gpIIIb, or gpIV. It is a member of the class B scavenger receptor family, expressed on platelets, monocytes, macrophages, megakaryocytes, microvasculature, dendritic cells and mammary endothelial cells. The primary ligands for CD36 have been reported to be oxidized low density lipoprotein, anionic phospholipids, and collagens I, IV, and V. CD36 acts as a scavenger receptor thus promoting the removal of apoptotic neutrophils and other apoptotic bodies, as well as clearance of defective erythrocytes.
100μg
Verified Reactivity: Mouse
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Mouse CD36/NIH-3T3 cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)
Application References(PubMed link indicates BioLegend citation): 1. Tsugita M. et al. 2017. Cell Rep. 18:1298. (FC and IHC-F)
RRID: AB_3097246 (BioLegend Cat. No. 163003) AB_3097246 (BioLegend Cat. No. 163004)
Structure: Scavenger receptor superfamily, 85 kD
Distribution: Platelets, monocytes, macrophages, microvascular and mammary endothelial cells
Function: Scavenger receptor, recognition and phagocytosis of apoptotic neutrophils, adhesion
Interaction: Endothelial cells, Macrophages, Monocytes, Platelets
Ligand/Receptor: Oxidized low density lipoprotein, anionic phospholipids, collagen I, IV, and V
Cell Type: Macrophages, Monocytes, Platelets
Biology Area: Cell Biology, Immunology
Molecular Family: CD Molecules
Antigen References: Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. Greenwalt DE, et al. 1992. Blood. 80:1105. Endemann G, et al. 1993. J Biol Chem. 268:11811.
Gene ID: 12491
UniProt: View information about CD36 on UniProt.org
Clone: ZND36-6
Regulatory Status: RUO
Other Names: FAT, gpIIIb, gpIV
Isotype: Rat IgG2a, κ