Biolegend, 339102, Purified anti-human CD355 (CRTAM) Antibody, 100μg

CRTAM, (class-I MHC-restricted T-cell associated molecule), is homodimer protein belonging to Ig superfamily. It is expressed transiently on activated NK cells,NKT cells and a subset of CD8+ T cells. Nectin-like molecule-2 (Necl2, TSCL1) is the ligand of CRTAM. CRTAM plays an important role in cell adhesion and migration.
100μg
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Immunogen: CRTAM-P815 cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Application References(PubMed link indicates BioLegend citation): Kent S, et al. 2005. Blood. 106:779
RRID: AB_1501238 (BioLegend Cat. No. 339102)
Structure: Dimer, Ig superfamily
Distribution: Activated NK cells and subset of CD8+ cells
Function: Adhesion and migration
Ligand/Receptor: Nectin-like molecule 2 (Necl2)
Cell Type: NK cells, T cells
Biology Area: Immunology
Molecular Family: Adhesion Molecules, CD Molecules, MHC Antigens
Antigen References: 1. Arase N, et al. 2005. Intl. Immunol. 17:1227 2. Kennedy J, et al. 2000. J. Leukoc. Biol. 67:725
Gene ID: 56253
UniProt: View information about CD355 on UniProt.org
Clone: Cr24.1
Regulatory Status: RUO
Other Names: Class I-MHC-Restricted T-cell Associated Molecule
Isotype: Mouse IgG2a, κ