Biolegend, 349203, PE anti-human TCR Vβ9 Antibody, 25tests

Vβ9 T cell receptor (TCR Vβ9) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of αβ + T cells. The TCR α/β recognizes peptides presented by the MHC molecules and initiates T cell mediated immune responses. Vβ9 + T cells are activated by the staphylococcal enterotoxin A (SEA).
25tests
Verified Reactivity: Human
Antibody Type: Monoclonal
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Application References(PubMed link indicates BioLegend citation): Labrecque N, et al. 1993. J. Exp. Med. 177:1735. (FC) Ciurli C, et al. 1998. J. Exp. Med. 187:253. (FC) Lavoie PM, et al. 2005. Int. Immunol. 17:931. (FC)
RRID: AB_10640740 (BioLegend Cat. No. 349204)
Structure: Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex
Distribution: subset of TCR αβ+ T cells
Function: Recognition of peptides presented by MHC molecules, responsible for T cell mediated immune response
Ligand/Receptor: MHC-peptide complex
Cell Type: T cells
Biology Area: Adaptive Immunity, Immunology
Molecular Family: TCRs
Antigen References: 1. Newton DW, et al. 1996. J. Immunol. 157:3988. 2. Marrack P, et al. 2008. Annu. Rev. Immunol. 26:171. 3. Thompson CB. 1995. Immunity 3:531. 4. Krogsgaard M and Davis MM. 2005. Nat. Immunol. 6:239.
Gene ID: 6957
UniProt: View information about TCR Vbeta9 on UniProt.org
Clone: MKB1
Regulatory Status: RUO
Other Names: T cell receptor Vbeta 9
Isotype: Mouse IgG1, λ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.