Biolegend, 381303, PE anti-human EMR1 Recombinant Antibody, 25tests

EGF-like module-containing mucin-like hormone receptor-like 1, also known as F4/80, is characterized as a member of the epidermal growth factor (EGF)-transmembrane 7 (TM7) family. Unlike its murine counterpart, which is widely used as a murine macrophage marker, the expression of human EMR1 is specific to eosinophils. Due to the restricted expression of EMR1, EMR1 is used as a therapeutic target for eosinophilic disorders.
25tests
Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
Preparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation Laser: Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID: AB_2922614 (BioLegend Cat. No. 381303) AB_2922614 (BioLegend Cat. No. 381304)
Structure: Seven transmembrane regions six EDF-like modules
Distribution: Eosinophils
Antigen References: Hamman J, et al. 2007. Eur J Immuno. 37:5797-2802.
Gene ID: 2015
UniProt: View information about EMR1 on UniProt.org
Clone: QA19A76
Regulatory Status: RUO
Other Names: EMR1, ADGRE1, TM7LN3
Isotype: Mouse IgG1, κ
Q: What type of PE do you use in your conjugates?
A: We use R-PE in our conjugates.