Biolegend, 383602, Purified anti-human BLTR Recombinant Antibody, 100μg

Leukotriene B4 receptor (BLTR or LTB4R-1), is a G protein-coupled receptor. It functions as a leukocyte chemoattractant. It activates the G1 family of the G proteins to mediate chemotaxis and it also uses G proteins to mediate cytotoxic activities. BLTR plays an important role in the recruitment and retention of leukocytes, primarily eosinophils.
100μg
Verified Reactivity: Human
Antibody Type: Recombinant
Host Species: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/mL
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2927873 (BioLegend Cat. No. 383602)
Structure: G protein-coupled receptor
Distribution: Granulocytes, Monocytes, Dendritic cells
Function: Leukocyte chemoattractant
Ligand/Receptor: Leukotriene B4
Cell Type: Basophils, Epithelial cells, Granulocytes, Leukocytes, Mast cells, Monocytes, Neutrophils
Biology Area: Cell Biology, Immunology
Molecular Family: GPCR, Innate Immune Signaling
Antigen References: Yokomizo Y, et al. 1997. Nature. 387:620-4 Lundeen KA, et al. 2006. J Immunol. 177:3439-47
Gene ID: 1241
UniProt: View information about BLTR on UniProt.org
Clone: QA20A70
Regulatory Status: RUO
Other Names: LTB4R, BLT1, LTBR1, LTB4R1, Leukotriene B4 Receptor
Isotype: Mouse IgG2a, κ